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Article

Recent advances in genetic predisposition to clinical acute lung injury.

American journal of physiology. Lung cellular and molecular physiology - 1 May 2009

Gao Li, Barnes Kathleen C

Abstract excerpt

It has been well established that acute lung injury (ALI), and the more severe presentation of acute respiratory distress syndrome (ARDS), constitute complex traits characterized by a multigenic and multifactorial etiology. Identification and validation of genetic variants contributing to disease susceptibility and severity has been hampered by the profound heterogeneity of the clinical phenotype and the role of...

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Identifiers

PMID: 19218355
DOI: 10.1152/ajplung.90269.2008
PMCID: PMC2681344

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