Article
Mouse models of obesity.
Clinics in dermatology - 1 Jan 2000
Carroll Levi, Voisey Joanne, van Daal Angela
Abstract excerpt
Insights into the etiology of human obesity have arisen from the study of animal models. Animal models of obesity are also important for the development of future treatments of obesity. An agouti mouse mutation resulting in obese, yellow mice was described over a century ago and in 1992 agouti was cloned, making it the first obesity gene characterized at the molecular level. The lethal yellow mouse mutation is...
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