Pro-opiomelanocortin and weight regulation: from mice to men.

Abstract excerpt

Significant progress in our understanding of the mechanisms of weight homeostasis has been made by studying the many genetic mouse models of obesity. Positional cloning in the obese mouse led to the discovery of leptin as a feedback messenger indicating the adequacy of peripheral energy stores. This was the first in a series of important advances in this field. Shortly after this discovery, two research...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Agouti-Related Protein
• Share to Agouti Signaling Protein
• Share to Body Weight