Article
Overexpression of the alternative oxidase restores senescence and fertility in a long-lived respiration-deficient mutant of Podospora anserina.
Molecular microbiology - 1 Dec 2001
Lorin S, Dufour E, Boulay J, Begel O, Marsy S, Sainsard-Chanet A
Abstract excerpt
Several lines of evidence have implicated reactive oxygen species (ROS) in the pathogenesis of various degenerative diseases and in organismal ageing. Furthermore, it has been shown recently that the alternative pathway respiration present in plants lowers ROS mitochondrial production. An alternative oxidase (AOXp) also occurs in the filamentous fungus Podospora anserina. We show here that overexpression of this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
