Article
Calorie restriction in the filamentous fungus Podospora anserina.
Experimental gerontology - 1 Aug 2010
van Diepeningen Anne D, Slakhorst S Marijke, Koopmanschap A Bertha, Ikink Gerjon J, Debets Alfons J M, Hoekstra Rolf F
Abstract excerpt
Calorie restriction (CR) is a regimen of reduced food intake that, although the underlying mechanism is unknown, in many organisms leads to life span extension. Podospora anserina is one of the few known ageing filamentous fungi and the ageing process and concomitant degeneration of mitochondria have been well-studied. CR in P. anserina increases not only life span but also forestalls the ageing-related decline...
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