Article
A causal link between respiration and senescence in Podospora anserina.
Proceedings of the National Academy of Sciences of the United States of America - 11 Apr 2000
Dufour E, Boulay J, Rincheval V, Sainsard-Chanet A
Abstract excerpt
Senescence, a progressive degenerative process leading to age-related increase in mortality, is found in most eukaryotes. However, the molecular events underlying aging remain largely unknown. Understanding how longevity is regulated is a fundamental problem. Here we demonstrate that the respiratory function is a key factor that contributes to shortening lifespan of the filamentous fungus Podospora anserina. In...
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