Article
Impact of a disruption of a pathway delivering copper to mitochondria on Podospora anserina metabolism and life span.
Eukaryotic cell - 1 Feb 2004
Stumpferl Stefan W, Stephan Oliver, Osiewacz Heinz D
Abstract excerpt
A global depletion of cellular copper as the result of a deficiency in high-affinity copper uptake was previously shown to affect the phenotype and life span of the filamentous fungus Podospora anserina. We report here the construction of a strain in which the delivery of copper to complex IV of the mitochondrial respiratory chain is affected. This strain, PaCox17::ble, is a PaCox17-null mutant that does not...
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