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Article

hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis.

Molecular and cellular biology - 1 Apr 2002

Iervolino Angela, Santilli Giorgia, Trotta Rossana, Guerzoni Clara, Cesi Vincenzo, Bergamaschi Anna, Gambacorti-Passerini Carlo, Calabretta Bruno, Perrotti Danilo

Abstract excerpt

hnRNP A1 is a nucleocytoplasmic shuttling heterogeneous nuclear ribonucleoprotein that accompanies eukaryotic mRNAs from the active site of transcription to that of translation. Although the importance of hnRNP A1 as a regulator of nuclear pre-mRNA and mRNA processing and export is well established, it is unknown whether this is relevant for the control of proliferation, survival, and differentiation of normal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11884611
DOI: 10.1128/MCB.22.7.2255-2266.2002
PMCID: PMC133663

Genes

BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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