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Article

NUP98 dysregulation in myeloid leukemogenesis.

Annals of the New York Academy of Sciences - 1 Jun 2007

Moore M A S, Chung K Y, Plasilova M, Schuringa J J, Shieh J-H, Zhou P, Morrone G

Abstract excerpt

Nucleoporin 98 (NUP98) is a component of the nuclear pore complex that facilitates mRNA export from the nucleus. It is mapped to 11p15.5 and is fused to a number of distinct partners, including nine members of the homeobox family as a consequence of leukemia-associated chromosomal translocations. NUP98-HOXA9 is associated with the t(7;11)(p15;p15) translocation in acute myeloid leukemia (AML), myelodysplastic...

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Topics

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Share to Antigens, CD34
Share to Chromosomes, Human, Pair 11
Share to Chromosomes, Human, Pair 7

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Loss of Heterozygosity

Share to Mice, Inbred NOD

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Source

Identifiers

PMID: 17442773
DOI: 10.1196/annals.1392.019

Genes

NUP98
HOXA9
MEIS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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NUP98 dysregulation in myeloid leukemogenesis.PMID 17442773Read ↗

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