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CXCL13/CXCR5 Chemokine Axis Promotes CXCR5 <sup>+</sup> CD19 <sup>+</sup> B-Cell and Follicular/Effector CXCR5 <sup>+</sup> CD4 <sup>+</sup> T-Cell Responses in the Lungs Associated with Protection from Severe and Fatal COVID-19 Following Infection with Pathogenic SARS-CoV-2 Delta Variant

2025-04-22

Abstract excerpt

<h4>ABSTRACT</h4> Chemokines play an important role in shaping lung innate and adaptive immunity to pulmonary infections and diseases. However, the role of CXC ligand 13 (CXCL13), a chemokine homeostatically produced by various lung cell types, in the protection from SARS-CoV-2 infection and disease remains controversial. Some studies reported that asymptomatic patients who survived severe COVID-19 had CXCL13-dom...

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Literature Corpus work
19560072-9ac4-51fa-bd93-e4b4512a296a
DOI
10.1101/2025.04.18.649623
Open publication

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CXCL13/CXCR5 Chemokine Axis Promotes CXCR5 <sup>+</sup> CD19 <sup>+</sup> B-Cell and Follicular/Effector CXCR5 <sup>+</sup> CD4 <sup>+</sup> T-Cell Responses in the Lungs Associated with Protection from Severe and Fatal COVID-19 Following Infection with Pathogenic SARS-CoV-2 Delta VariantDOI 10.1101/2025.04.18.649623
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