Article
In search of cardiovascular candidate genes: interactions between phenotypes and genotypes.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2002
Deschepper Christian F, Boutin-Ganache Isabelle, Zahabi Ahmad, Jiang Zhibin
Abstract excerpt
Most cardiovascular traits of interest can be defined as "complex traits," with the first step in the identification of genetic factors affecting such traits being the detection of quantitative trait loci (QTLs). Animal models have proven particularly useful in this regard. However, only very few of the QTLs identified to date have led to the identification of candidate genes. We describe an example of our own...
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