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Article

Pulsatile growth hormone secretion persists in genetic growth hormone-releasing hormone resistance.

American journal of physiology. Endocrinology and metabolism - 1 Apr 2002

Maheshwari Hiralal G, Pezzoli Suzan S, Rahim Asad, Shalet Stephen M, Thorner Michael O, Baumann Gerhard

Abstract excerpt

Growth hormone (GH) secretion is regulated by GH-releasing hormone (GHRH), somatostatin, and possibly ghrelin, but uncertainty remains about the relative contributions of these hypophysiotropic factors to GH pulsatility. Patients with genetic GHRH receptor (GHRH-R) deficiency present an opportunity to examine GH secretory dynamics in the selective absence of GHRH input. We studied circadian GH profiles in four...

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Source

Identifiers

PMID: 11882517
DOI: 10.1152/ajpendo.00537.2001

Genes

GHRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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