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Article

Genetic control of 24-hour growth hormone secretion in man: a twin study.

The Journal of clinical endocrinology and metabolism - 1 Mar 1999

Mendlewicz J, Linkowski P, Kerkhofs M, Leproult R, Copinschi G, Van Cauter E

Abstract excerpt

The aim of this study was to delineate the contributions of genetic and environmental factors in the regulation of the 24-h GH secretion. The 24-h profile of plasma GH was obtained at 15-min intervals in 10 pairs of monozygotic and 9 pairs of dizygotic normal male twins, aged 16-34 yr. Sleep was polygraphically monitored. Significant pulses of GH secretion were identified using a modification of the computer...

Topics

Adolescent
Adult
Anthropometry
Circadian Rhythm
Genetic Variation
Human Growth Hormone
Humans
Male
Sleep
Twins, Dizygotic
Twins, Monozygotic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 10084561
DOI: 10.1210/jcem.84.3.5525

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