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Article

Mks1 in concert with TOR signaling negatively regulates RTG target gene expression in S. cerevisiae.

Current biology : CB - 5 Mar 2002

Dilova Ivanka, Chen Ching-Yi, Powers Ted

Abstract excerpt

The target of rapamycin (TOR) signaling pathway allows eukaryotic cells to regulate their growth in response to nutritional cues. In S. cerevisiae, TOR controls the expression of genes involved in several nutrient-responsive biosynthetic pathways. In particular, we have demonstrated that TOR negatively regulates a concise cluster of genes (termed RTG target genes) that encode mitochondrial and peroxisomal enzymes...

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Source

Identifiers

PMID: 11882290
DOI: 10.1016/s0960-9822(02)00677-2

Genes

MKS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Mks1 in concert with TOR signaling negatively regulates RTG target gene expression in S. cerevisiae.PMID 11882290Read ↗

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Tor signaling and nutrient-based signals converge on Mks1p phosphorylation to regulate expression of Rtg1.Rtg3p-dependent target genes.Semantic proximity Read ↗

Stress-response transcription factors Msn2 and Msn4 couple TORC2-Ypk1 signaling and mitochondrial respiration to ATG8 gene expression and autophagySemantic proximity Read ↗

The TOR signaling cascade regulates gene expression in response to nutrients.Semantic proximity Read ↗

Differential phosphorylation of a regulatory subunit of protein kinase CK2 by target of rapamycin complex 1 signaling and the Cdc-like kinase Kns1.Semantic proximity Read ↗

TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae.Semantic proximity Read ↗

Chemical Genetics of Rapamycin-Insensitive TORC2 in S. cerevisiaeSemantic proximity Read ↗

TORC1 signaling is governed by two negative regulators in fission yeast.Semantic proximity Read ↗

A novel degron-mediated degradation of the RTG pathway regulator, Mks1p, by SCFGrr1.Semantic proximity Read ↗

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