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Article

Accounting for strain-specific differences during RTG target gene regulation in Saccharomyces cerevisiae.

FEMS yeast research - 1 Jan 2006

Dilova Ivanka, Powers Ted

Abstract excerpt

Mitochondrial dysfunction results in the expression, via the retrograde response pathway, of a concise set of genes (RTG target genes) that encode enzymes involved in the anapleurotic production of alpha-ketoglutarate. Inhibiting the rapamycin-sensitive TOR kinases, important regulators of cell growth, similarly results in RTG target gene expression under rich nutrient conditions. Retrograde and TOR-dependent...

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Source

Identifiers

PMID: 16423076
DOI: 10.1111/j.1567-1364.2005.00008.x

Genes

MKS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Accounting for strain-specific differences during RTG target gene regulation in Saccharomyces cerevisiae.PMID 16423076Read ↗

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Tor signaling and nutrient-based signals converge on Mks1p phosphorylation to regulate expression of Rtg1.Rtg3p-dependent target genes.Semantic proximity Read ↗

Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors.Semantic proximity Read ↗

The retrograde response links metabolism with stress responses, chromatin-dependent gene activation, and genome stability in yeast aging.Semantic proximity Read ↗

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