Article
Altered water barrier function in epidermal-type fatty acid binding protein-deficient mice.
The Journal of investigative dermatology - 1 Mar 2002
Owada Yuji, Takano Hiroshi, Yamanaka Hitomi, Kobayashi Hiromi, Sugitani Yoshinobu, Tomioka Yoshihisa, Suzuki Ichiro, Suzuki Ryoji, Terui Tadashi, Mizugaki Michinao, Tagami Hachiro, Noda Tetsuo, Kondo Hisatake
Abstract excerpt
We have generated mutant mice for epidermal-type fatty acid binding protein by the gene targeting technique and examined the phenotype in detail. Despite a lack in the expression of epidermal-type fatty acid binding protein mRNA and its protein in the skin and other tissues of the mutant mice, the animals appeared normal in gross and histologic examination. Northern blot analysis of other fatty acid binding...
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