Article
Analysis on the phenotype of E-FABP-gene knockout mice.
Molecular and cellular biochemistry - 1 Oct 2002
Owada Yuji, Suzuki Ichiro, Noda Tetsuo, Kondo Hisatake
Abstract excerpt
The fatty acids are shown to be critical in the maintenance of the water permeability barrier that is ascribed to the lipids in the intracellular milieu of the cornified cell layer in the epidermis. In view of this importance in the skin, we examined the phenotype of epidermal fatty acid binding protein (E-FABP)-deficient mice. In spite of total lack of E-FABP expression in the various tissues of E-FABP deficient...
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