Article
Functional and phenotypic analysis of lymphocytes in head and neck cancer.
Archives of otolaryngology--head & neck surgery - 1 Aug 1991
Snyderman C H, Heo D S, Johnson J T, D'Amico F, Barnes L, Whiteside T L
Abstract excerpt
We compared the phenotype and antitumor effector function of lymphocytes obtained from tumor tissues, lymph nodes, and the peripheral blood of patients with head and neck cancer. Freshly isolated tumor-infiltrating lymphocytes were deficient in CD4+ T cells in comparison with lymph node lymphocytes (LNL) and peripheral blood lymphocytes. A significantly higher CD4/CD8 ratio observed in LNL vs tumor-infiltrating...
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