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Article

CD62L Is a Functional and Phenotypic Marker for Circulating Innate Lymphoid Cell Precursors

30 Nov 2018

Abstract excerpt

Abstract Innate lymphoid cells (ILCs) guard epithelial tissue integrity during homeostasis, but can be potent immune effector cells during inflammation. Precursors to all ILC subsets (ILC precursors [ILCP]) have been identified in human peripheral blood (PB). We found that during homeostasis, ILCP in PB of mouse and human expressed homing receptors for secondary lymphoid organs, mainly CD62L. These ILCP entered...

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PMID: 30504420
DOI: 10.4049/jimmunol.1701153

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