Article
Selective homing of phenotypically lytic cells within nasopharyngeal carcinoma biopsies: numerous CD8- and CD16-positive cells in the tumor.
International journal of cancer - 22 Apr 1991
Lakhdar M, Ben Aribia M H, Maalej M, Ladgham A
Abstract excerpt
We present a comparative analysis of cell-mediated immunity between circulating lymphocytes and tumor-infiltrating lymphocytes (TIL) from patients with nasopharyngeal carcinoma (NPC). Phenotypic analysis using a panel of monoclonal antibodies (MAbs) to define lymphocytic subsets has revealed a selective homing of phenotypically lytic cells such as CD8- and CD16-positive cells, but a low percentage of macrophages...
Topics
- Antigens, CD
- Antigens, Differentiation
- Antigens, Differentiation, T-Lymphocyte
- Biopsy
- CD8 Antigens
- Cytotoxicity, Immunologic
- Humans
- Killer Cells, Natural
- Lectins
- Lymphocyte Activation
