Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of cytotoxicity and gain of cytokine production in murine tumor-activated NK cells.

PloS one - 1 Jan 2014

Müller Jürgen R, Waldmann Thomas A, Dubois Sigrid

Abstract excerpt

NK cells are able to form a functional memory suggesting that some NK cells are surviving the activation process. We hypothesized that NK cell activation causes the development of a distinct NK cell subset and studied the fate of murine post-activation NK cells. Activation was achieved by in vivo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coculture Techniques
Share to Cytotoxicity, Immunologic
Share to Granulocyte-Macrophage Colony-Stimulating Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Granzymes

Share to Interleukin-15

Share to Interleukin-2

Share to Melanoma, Experimental

Share to Perforin

Source

Open in PubMed Open full text

Identifiers

PMID: 25101668
DOI: 10.1371/journal.pone.0102793
PMCID: PMC4125151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25101668-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of cytotoxicity and gain of cytokine production in murine tumor-activated NK cells.PMID 25101668Read ↗

Unraveling exhaustion in adaptive and conventional NK cellsSemantic proximity Read ↗

The diversity of natural killer cell functional and phenotypic states in cancer.Semantic proximity Read ↗

PD-1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma.Semantic proximity Read ↗

The breast tumor microenvironment alters the phenotype and function of natural killer cells.Semantic proximity Read ↗

An Uncoupling of Canonical Phenotypic Markers and Functional Potency of Ex Vivo-Expanded Natural Killer Cells.Semantic proximity Read ↗

NK Cells in a Tug-of-War With Cancer: The Roles of Transcription Factors and Cytoskeleton.Semantic proximity Read ↗

Human natural killer (NK) cells: requirements for cell proliferation and expansion of phenotypically novel subpopulations.Semantic proximity Read ↗

NK cell proliferation and inflammation.Semantic proximity Read ↗

Rapid establishment of a tumor-retained state curtails the contribution of conventional NK cells to anti-tumor immunity in solid cancersSemantic proximity Read ↗

Phenotypically and functionally distinct subsets of natural killer cells in human PBMCs.Semantic proximity Read ↗

NKT and T cells: coordinate regulation of NK-like phenotype and cytokine production.Semantic proximity Read ↗

Indirect Impact of PD-1/PD-L1 Blockade on a Murine Model of NK Cell Exhaustion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.