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Article

A pre-anaphase role for a Cks/Suc1 in acentrosomal spindle formation of Drosophila female meiosis.

EMBO reports - 1 Nov 2005

Pearson Neil J, Cullen C Fiona, Dzhindzhev Nikola S, Ohkura Hiroyuki

Abstract excerpt

Conventional centrosomes are absent from a female meiotic spindle in many animals. Instead, chromosomes drive spindle assembly, but the molecular mechanism of this acentrosomal spindle formation is not well understood. We have screened female sterile mutations for defects in acentrosomal spindle formation in Drosophila female meiosis. One of them, remnants (rem), disrupted bipolar spindle morphology and...

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Identifiers

PMID: 16170306
DOI: 10.1038/sj.embor.7400529
PMCID: PMC1371029

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