Article
The drosophila protein asp is involved in microtubule organization during spindle formation and cytokinesis.
The Journal of cell biology - 14 May 2001
Wakefield J G, Bonaccorsi S, Gatti M
Abstract excerpt
Abnormal spindle (Asp) is a 220-kD microtubule-associated protein from Drosophila that has been suggested to be involved in microtubule nucleation from the centrosome. Here, we show that Asp is enriched at the poles of meiotic and mitotic spindles and localizes to the minus ends of central spindle microtubules. Localization to these structures is independent of a functional centrosome. Moreover, colchicine...
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