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Article

Sequence stability of the gene encoding outer membrane protein P2 of nontypeable Haemophilus influenzae in the human respiratory tract.

The Journal of infectious diseases - 1 Mar 2002

Hiltke Thomas J, Sethi Sanjay, Murphy Timothy F

Abstract excerpt

Nontypeable Haemophilus influenzae (NTHI) is an important cause of lower respiratory tract infections in patients with chronic obstructive pulmonary disease. Recent findings suggest that the major outer membrane protein P2 should be reconsidered as a vaccine candidate for NTHI. A P2-based vaccine would require a relative degree of sequence stability of the gene encoding P2 (ompP2) during colonization. To...

Topics

Amino Acid Sequence
Bacterial Outer Membrane Proteins
Bacterial Proteins
Base Sequence
Genetic Variation
Haemophilus Infections
Haemophilus influenzae
Humans
Molecular Sequence Data
Porins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pulmonary Disease, Chronic Obstructive

Respiratory Tract Infections

Sequence Analysis, DNA

Source

Identifiers

PMID: 11865419
DOI: 10.1086/339362

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Sequence stability of the gene encoding outer membrane protein P2 of nontypeable Haemophilus influenzae in the human respiratory tract.PMID 11865419Read ↗

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