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Article

Mapping of a strain-specific bactericidal epitope to the surface-exposed loop 5 on the P2 porin protein of non-typeable Haemophilus influenzae.

Microbial pathogenesis - 1 Oct 1994

Yi K, Murphy T F

Abstract excerpt

The P2 protein is the major outer-membrane protein of non-typeable Haemophilus influenzae (NTHI) and shows extreme heterogeneity among strains. Based on the analysis of antigenic structure, the P2 protein consists of eight potentially surface-exposed loops. Previous studies of monoclonal antibodies (mABs) to a single strain of NTHI showed that P2 contains potentially immunodominant epitopes in loop 5 of the...

Topics

Adult
Amino Acid Sequence
Antibodies, Monoclonal
Bacterial Outer Membrane Proteins
Base Sequence
Cloning, Molecular
DNA Primers
Epitopes
Haemophilus influenzae
Humans
Immunodominant Epitopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Porins

Species Specificity

Source

Identifiers

PMID: 7536289
DOI: 10.1006/mpat.1994.1073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7536289-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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