Variation in the composition and pore function of major outer membrane pore protein P2 of Haemophilus influenzae from cystic fibrosis patients.

doi:10.1128/AAC.43.2.226

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Article

Variation in the composition and pore function of major outer membrane pore protein P2 of Haemophilus influenzae from cystic fibrosis patients.

Antimicrobial agents and chemotherapy - 1 Feb 1999

Regelink A G, Dahan D, Möller L V, Coulton J W, Eijk P, Van Ulsen P, Dankert J, Van Alphen L

Abstract excerpt

We investigated the relationship between susceptibility to beta-lactam antibiotics and variation in the major outer membrane protein P2 (OmpP2; also called porin) of persistent nonencapsulated Haemophilus influenzae isolated from cystic fibrosis patients. Nine OmpP2 variants were selected from two distinct H. influenzae strains from two patients extensively treated with beta-lactam antibiotics. The variants...

Topics

Amino Acid Sequence
Bacterial Outer Membrane Proteins
Bacterial Proteins
Carrier Proteins
Cystic Fibrosis
DNA, Bacterial
Genetic Variation
Haemophilus influenzae
Hexosyltransferases
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microbial Sensitivity Tests

Molecular Sequence Data

Muramoylpentapeptide Carboxypeptidase

Penicillin-Binding Proteins

Peptidyl Transferases

Sequence Homology, Amino Acid

Source

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Identifiers

PMID: 9925510
DOI: 10.1128/AAC.43.2.226
PMCID: PMC89055

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Variation in the composition and pore function of major outer membrane pore protein P2 of Haemophilus influenzae from cystic fibrosis patients.PMID 9925510Read ↗

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