Article
Characterization of a mutant of Haemophilus influenzae type b lacking the P2 major outer membrane protein.
Infection and immunity - 1 Oct 1990
Cope L D, Pelzel S E, Latimer J L, Hansen E J
Abstract excerpt
An isogenic mutant of Haemophilus influenzae type b (Hib) lacking the ability to express the P2 major outer membrane (porin) protein was constructed and characterized in various model systems. Linker insertion mutagenesis of a cloned Hib DNA insert containing the P2 structural gene was used in conjunction with a genetic transformation system to obtain a transformant unreactive with a P2-specific monoclonal...
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