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Article

MutY and MutY homologs (MYH) in genome maintenance.

Frontiers in bioscience : a journal and virtual library - 1 Sept 2006

Lu A-Lien, Bai Haibo, Shi Guoli, Chang Dau-Yin

Abstract excerpt

The base excision repair carried out by bacterial MutY DNA glycosylase and eukaryotic MutY homolog (MYH) is responsible for removing adenines misincorporated into DNA opposite G and 7,8-dihydro-8-oxo-guanines (8-oxoG); thereby preventing G:C to T:A mutations. Escherichia coli MutY (EcMutY) can also remove adenines from A/C and A/5-hydroxyuracil and can remove guanines from G/8-oxoG mismatches at reduced rates....

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Source

Identifiers

PMID: 16720376
DOI: 10.2741/2033

Genes

APC
MSH2
MSH6
PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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