Article
The tumor suppressor homolog in fission yeast, myh1(+), displays a strong interaction with the checkpoint gene rad1(+).
Mutation research - 26 Sept 2008
Jansson Kristina, Warringer Jonas, Farewell Anne, Park Han-Oh, Hoe Kwang-Lae, Kim Dong-Uk, Hayles Jacqueline, Sunnerhagen Per
Abstract excerpt
The DNA glycosylase MutY is strongly conserved in evolution, and homologs are found in most eukaryotes and prokaryotes examined. This protein is implicated in repair of oxidative DNA damage, in particular adenine mispaired opposite 7,8-dihydro-8-oxoguanine. Previous investigations in Escherichia...
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