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Article

A change in the structure of Vbeta chromatin associated with TCR beta allelic exclusion.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2002

Tripathi Rajkamal, Jackson Annette, Krangel Michael S

Abstract excerpt

To investigate chromatin control of TCR beta rearrangement and allelic exclusion, we analyzed TCR beta chromatin structure in double negative (DN) thymocytes, which are permissive for TCR beta recombination, and in double positive (DP) thymocytes, which are postallelic exclusion and nonpermissive for Vbeta to DbetaJbeta recombination. Histone acetylation mapping and DNase I sensitivity studies indicate Vbeta and...

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Source

Identifiers

PMID: 11859121
DOI: 10.4049/jimmunol.168.5.2316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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