Article
A Monocyte chemoattractant protein-1 (MCP-1) polymorphism and outcome after renal transplantation.
Journal of the American Society of Nephrology : JASN - 1 Oct 2002
Krüger Bernd, Schröppel Bernd, Ashkan Rami, Marder Brad, Zülke Carl, Murphy Barbara, Krämer Bernhard K, Fischereder Michael
Abstract excerpt
Among the factors modulating transplant rejection and cardiovascular disease, chemokines and their respective receptors deserve special attention. In this respect, increased expression of MCP-1 and the corresponding receptor CCR2 have been demonstrated in renal transplant rejection and coronary artery disease. The impact of the MCP-1-2518G and CCR2-64I genotypes on renal allograft function was investigated in 232...
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