Article
The effect of chemokine receptor gene polymorphisms (CCR2V64I, CCR5-59029G>A and CCR5Δ32) on renal allograft survival in Pakistani transplant patients.
Gene - 15 Dec 2012
Firasat Sadaf, Raza Ali, Abid Aiysha, Aziz Tahir, Mubarak Mohammad, Naqvi Syed Ali Anwar, Rizvi Syed Adeebul Hasan, Mehdi Syed Qasim, Khaliq Shagufta
Abstract excerpt
BACKGROUND: Gene polymorphisms of the chemokine receptors CCR2 and CCR5 (CCR2V64I, CCR5-59029G>A and CCR5Δ32) have been shown to be associated with renal allograft rejection. The aim of this study was to investigate the association of these polymorphisms with allograft rejection among Pakistani transplant patients. METHOD: A total of 606 renal transplant patients and an equal number of their donors were included...
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