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Article

Regulation of Purkinje cell alignment by reelin as revealed with CR-50 antibody.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 May 1997

Miyata T, Nakajima K, Mikoshiba K, Ogawa M

Abstract excerpt

Cerebellar Purkinje cells are generated in the ventricular zone, migrate outward, and finally form a monolayer in the cortex. In reeler mice, however, most Purkinje cells cluster abnormally in subcortical areas. Reelin, the candidate reeler gene product recognized by the CR-50 monoclonal antibody...

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Share to Antibodies, Monoclonal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9133383
PMCID: PMC6573700

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9133383-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Regulation of Purkinje cell alignment by reelin as revealed with CR-50 antibody.PMID 9133383Read ↗

Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice.Semantic proximity Read ↗

Disruption of hippocampal development in vivo by CR-50 mAb against reelin.Semantic proximity Read ↗

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler.Semantic proximity Read ↗

Obstructed migration of Purkinje cells in the developing cerebellum of the reeler mutant mouse.Semantic proximity Read ↗

The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum.Semantic proximity Read ↗

Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody.Semantic proximity Read ↗

The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons.Semantic proximity Read ↗

Cerebellar disorganization characteristic of reeler in scrambler mutant mice despite presence of reelin.Semantic proximity Read ↗

Trajectory Analysis Unveils Reelin's Role in the Directed Migration of Granule Cells in the Dentate Gyrus.Semantic proximity Read ↗

Expression of reelin, the gene responsible for the reeler mutation, in embryonic development and adulthood in the mouse.Semantic proximity Read ↗

Development of commissural connections in the hippocampus of reeler mice: evidence of an inhibitory influence of Cajal-Retzius cells.Semantic proximity Read ↗

Rescue of the reeler phenotype in the dentate gyrus by wild-type coculture is mediated by lipoprotein receptors for Reelin and Disabled 1.Semantic proximity Read ↗

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