Article
Trajectory Analysis Unveils Reelin's Role in the Directed Migration of Granule Cells in the Dentate Gyrus.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Jan 2018
Wang Shaobo, Brunne Bianka, Zhao Shanting, Chai Xuejun, Li Jiawei, Lau Jeremie, Failla Antonio Virgilio, Zobiak Bernd, Sibbe Mirjam, Westbrook Gary L, Lutz David, Frotscher Michael
Abstract excerpt
Reelin controls neuronal migration and layer formation. Previous studies in reeler mice deficient in Reelin focused on the result of the developmental process in fixed tissue sections. It has remained unclear whether Reelin affects the migratory process, migration directionality, or migrating neurons guided by the radial glial scaffold. Moreover, Reelin has been regarded as an attractive signal because newly...
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