Article
Reconstructing parental genotypes when testing for linkage in the presence of association.
Theoretical population biology - 1 Nov 2001
Knapp M
Abstract excerpt
Various family-based association methods have recently been proposed that allow testing for linkage in the presence of linkage disequilibrium between a marker and a disease even if there is only incomplete parental-genotype information. For some families, it may be possible to reconstruct missing parental genotypes from the genotypes of their offspring. Treating such a reconstructed family as if parental...
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