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Article

Pedigree-based relationship inference from complex DNA mixtures.

International journal of legal medicine - 1 May 2017

Dørum Guro, Kaur Navreet, Gysi Mario

Abstract excerpt

We present a general method for analysing DNA mixtures involving relatives that accounts for dropout and drop-in, mutations, silent alleles and population substructure. Whether the aim is to identify the contributors to a mixture who may be related, or to determine the relationship between individuals based on a DNA mixture, both types of problems can be handled by the method and software presented here. We focus...

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PMID: 28101646
DOI: 10.1007/s00414-016-1526-x

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