Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel genetic system for analysis of co-activators for the N-terminal transactivation function domain of the human androgen receptor.

Bioscience, biotechnology, and biochemistry - 1 Jun 2004

Takeyama Ken-Ichi, Ito Saya, Sawatsubashi Shun, Shirode Yuko, Yamamoto Ayako, Suzuki Eriko, Maki Akio, Yamagata Kaoru, Zhao Yue, Kouzmenko Alexandre, Tabata Tetsuya, Kato Shigeaki

Abstract excerpt

Androgen receptor (hAR) regulates transcription of target genes in a ligand-dependent manner and recruits a number of co-activators for the ligand-induced transactivation via the N-terminal, activation function-1 (AF-1), and C-terminal, AF-2, transactivation domains. But the co-regulator functions on each of AR domains have not yet been fully understood. We have established a Drosophila transgenic system in which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Drosophila

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Methods

Share to Protein Structure, Tertiary

Share to Receptors, Androgen

Share to Sequence Deletion

Share to Trans-Activators

Share to Transcriptional Activation

Source

Identifiers

PMID: 15215582
DOI: 10.1271/bbb.68.1209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel genetic system for analysis of co-activators for the N-terminal transactivation function domain of the human androgen receptor.PMID 15215582Read ↗

Delineation of two distinct type 1 activation functions in the androgen receptor amino-terminal domain.Semantic proximity Read ↗

Androgen Receptor (AR) Coregulators: A Diversity of Functions Converging on and Regulating the AR Transcriptional ComplexSemantic proximity Read ↗

An androgen receptor NH2-terminal conserved motif interacts with the COOH terminus of the Hsp70-interacting protein (CHIP).Semantic proximity Read ↗

The Androgen Receptor Interacts with Multiple Regions of the Large Subunit of General Transcription Factor TFIIFSemantic proximity Read ↗

Functional interactions of the AF-2 activation domain core region of the human androgen receptor with the amino-terminal domain and with the transcriptional coactivator TIF2 (transcriptional intermediary factor2).Semantic proximity Read ↗

Diverse roles of androgen receptor (AR) domains in AR-mediated signalingSemantic proximity Read ↗

Ligand- and coactivator-mediated transactivation function (AF2) of the androgen receptor ligand-binding domain is inhibited by the cognate hinge region.Semantic proximity Read ↗

The yeast Ada complex mediates the ligand-dependent activation function AF-2 of retinoid X and estrogen receptors.Semantic proximity Read ↗

Mechanisms of androgen receptor signalling via steroid receptor coactivator-1 in prostate.Semantic proximity Read ↗

The Hinge Region Regulates DNA Binding, Nuclear Translocation, and Transactivation of the Androgen ReceptorSemantic proximity Read ↗

Identification and Characterization of ART-27, a Novel Coactivator for the Androgen Receptor N TerminusSemantic proximity Read ↗

Identification of a highly conserved domain in the androgen receptor that suppresses the DNA-binding domain-DNA interactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.