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Article

GRIP1 mediates the interaction between the amino- and carboxyl-termini of the androgen receptor.

Biological chemistry - 1 Jan 2005

Shen Howard C, Buchanan Grant, Butler Lisa M, Prescott Jennifer, Henderson Michael, Tilley Wayne D, Coetzee Gerhard A

Abstract excerpt

The androgen receptor (AR) mediates transactivation of target genes by acting as a dimer in which its amino-terminal domain (AR-NTD) interacts with its carboxyl-terminal, ligand-binding domain (AR-LBD) (N/C interaction). Here we assessed if and how AR N/C interaction relates to AR transactivation activity and how the p160 coactivator GRIP1 participates in both processes. The concentration of dihydrotestosterone...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15843149
DOI: 10.1515/BC.2005.009

Genes

GRIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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