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Article

ARA24/Ran enhances the androgen-dependent NH2- and COOH-terminal interaction of the androgen receptor.

Biochemical and biophysical research communications - 29 Aug 2008

Harada Naoki, Ohmori Yuji, Yamaji Ryoichi, Higashimura Yasuki, Okamoto Kazuki, Isohashi Fumihide, Nakano Yoshihisa, Inui Hiroshi

Abstract excerpt

The androgen receptor (AR) acts as an androgen-dependent transcription factor controlling the development of prostate tissue. Upon binding to androgen, AR undergoes a dynamic structural change leading to interaction between the NH(2)- and COOH-terminal regions of AR (N-C interaction). ARA24/Ran, which is a small GTPase, functions as an AR coactivator. Here, we report that ARA24/Ran enhances the N-C interaction of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18565325
DOI: 10.1016/j.bbrc.2008.06.024

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SRC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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