Article
Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations.
American journal of human genetics - 1 Apr 2004
Crawford Dana C, Carlson Christopher S, Rieder Mark J, Carrington Dana P, Yi Qian, Smith Joshua D, Eberle Michael A, Kruglyak Leonid, Nickerson Deborah A
Abstract excerpt
Recent studies have suggested that a significant fraction of the human genome is contained in blocks of strong linkage disequilibrium, ranging from ~5 to >100 kb in length, and that within these blocks a few common haplotypes may account for >90% of the observed haplotypes. Furthermore, previous studies have suggested that common haplotypes in candidate genes are generally shared across populations and represent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.