Article
Gene targeting of components of the fibrinolytic system.
Thrombosis and haemostasis - 1 Jan 2002
Ploplis Victoria A, Castellino Francis J
Abstract excerpt
A number of in vitro and in vivo observations have implicated components of the fibrinolytic system in events associated with diverse physiological and pathophysiological processes, ranging from embryo implantation to cancer. Advances in gene targeting technology have led to the generation of mice deficient for components of the fibrinolytic system. Remarkably, these animals survive to adulthood with few...
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