Gene targeting and gene transfer studies of the biological role of the plasminogen/plasmin system.

Abstract excerpt

A possible role of the plasminogen/plasmin or fibrinolytic system in several biological processes has been implied from correlations between fibrinolytic activity and (patho)physiological phenomena. However, such indirect evidence does not allow to definitively establish the biological relevance of this system. Two recently developed technologies, gene targeting and gene transfer, have allowed to more...

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