Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Positive darwinian selection promotes heterogeneity among members of the antifreeze protein multigene family.

Journal of molecular evolution - 1 Mar 2002

Swanson Willie J, Aquadro Charles F

Abstract excerpt

A variety of organisms have independently evolved proteins exhibiting antifreeze activity that allows survival at subfreezing temperatures. The antifreeze proteins (AFPs) bind ice nuclei and depress the freezing point by a noncolligative absorption-inhibition mechanism. Many organisms have a heterogeneous suite of AFPs with variation in primary sequence between paralogous loci. Here, we demonstrate that the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bayes Theorem
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fishes

Share to Likelihood Functions

Share to Multigene Family

Share to Selection, Genetic

Share to Sequence Alignment

Source

Identifiers

PMID: 11847566
DOI: 10.1007/s00239-001-0030-0

Genes

AFP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Positive darwinian selection promotes heterogeneity among members of the antifreeze protein multigene family.PMID 11847566Read ↗

Evolution of the diverse antifreeze proteins.Semantic proximity Read ↗

Functional diversification and evolution of antifreeze proteins in the antarctic fish Lycodichthys dearborni.Semantic proximity Read ↗

Engineering a naturally inactive isoform of type III antifreeze protein into one that can stop the growth of ice.Semantic proximity Read ↗

Structural investigation, computational analysis, and theoretical cryoprotectant approach of antifreeze protein type IV mutants.Semantic proximity Read ↗

Structure and function of an antifreeze polypeptide from ocean pout, Macrozoarces americanus: role of glutamic acid residues in protein stability and antifreeze activity by site-directed mutagenesis.Semantic proximity Read ↗

Structure of type I antifreeze protein and mutants in supercooled water.Semantic proximity Read ↗

Type I 'antifreeze' proteins. Structure-activity studies and mechanisms of ice growth inhibition.Semantic proximity Read ↗

Biophysical and biochemical aspects of antifreeze proteins: Using computational tools to extract atomistic information.Semantic proximity Read ↗

Effect of a mutation on the structure and dynamics of an alpha-helical antifreeze protein in water and ice.Semantic proximity Read ↗

Hydrophobic ice-binding sites confer hyperactivity of an antifreeze protein from a snow mold fungus.Semantic proximity Read ↗

The biological function of an insect antifreeze protein simulated by molecular dynamics.Semantic proximity Read ↗

Characterization of microbial antifreeze protein with intermediate activity suggests that a bound-water network is essential for hyperactivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.