Article
Functional diversification and evolution of antifreeze proteins in the antarctic fish Lycodichthys dearborni.
Journal of molecular evolution - 1 Aug 2010
Kelley Joanna L, Aagaard Jan E, MacCoss Michael J, Swanson Willie J
Abstract excerpt
Antifreeze proteins (AFPs) have independently evolved in many organisms. AFPs act by binding to ice crystals, effectively lowering the freezing point. AFPs are often at high copy number in a genome and diversity exists between copies. Type III antifreeze proteins are found in Arctic and Antarctic eel pouts, and have previously been shown to evolve under positive selection. Here we combine molecular and proteomic...
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