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Article

Structural investigation, computational analysis, and theoretical cryoprotectant approach of antifreeze protein type IV mutants.

European biophysics journal : EBJ - 1 Nov 2024

Eskandari Azadeh, Leow Thean Chor, Rahman Mohd Basyaruddin Abdul, Oslan Siti Nurbaya

Abstract excerpt

Antifreeze proteins (AFPs) have unique features to sustain life in sub-zero environments due to ice recrystallization inhibition (IRI) and thermal hysteresis (TH). AFPs are in demand as agents in cryopreservation, but some antifreeze proteins have low levels of activity. This research aims to improve the cryopreservation activity of an AFPIV. In this in silico study, the helical peptide afp1m from an Antarctic...

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Identifiers

PMID: 39327310
DOI: 10.1007/s00249-024-01719-7

Genes

AFP
TH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structural investigation, computational analysis, and theoretical cryoprotectant approach of antifreeze protein type IV mutants.PMID 39327310Read ↗

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