Article
P-glycoprotein expression in adult acute myeloid leukemia: correlation with induction treatment outcome.
Neoplasma - 1 Jan 2001
Tóthová E, Elbertová A, Fricová M, Kafková A, Hlebasková M, Svorcová E, Stecová N, Guman T, Raffac S
Abstract excerpt
Drug resistance has become a major cause of the treatment failure in patients with acute leukemia. P-glycoprotein (P-gp), which is associated with multidrug resistance (MDR) phenotype, has been reported to be an important predictor of the treatment outcome. The aim of this study was to analyze the value of P-gp expression in bone marrow cells as a predictor of the response to remission induction chemotherapy, as...
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