Variation of MDR proteins expression and activity levels according to clinical status and evolution of CML patients

doi:10.1002/cyto.b.20580

Article

Variation of MDR proteins expression and activity levels according to clinical status and evolution of CML patients

2 Dec 2010

Abstract excerpt

The involvement of the multidrug resistance (MDR) mediated by ABC transporter proteins P-glycoprotein (Pgp) and multidrug resistance-associated protein-1 (MRP1) overexpressions in patients with chronic myeloid leukemia (CML) are not completely understood. Pgp and MRP1 expressions and activity were analyzed in samples from 158 patients with chronic myeloid leukemia (CML). Using flow cytometry, Pgp expression was...

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