Article
P-glycoprotein expression in de novo acute myeloid leukemia.
Leukemia & lymphoma - 1 Oct 1997
Del Poeta G, Venditti A, Aronica G, Stasi R, Cox M C, Buccisano F, Bruno A, Tamburini A, Suppo G, Simone M D, Epiceno A M, Del Moro B, Masi M, Papa G, Amadori S
Abstract excerpt
Detection of the multidrug resistance P-glycoprotein (PGP) phenotype was performed at the time of diagnosis in 223 patients with acute myeloid leukemia (AML) by flow cytometry using C219 Monoclonal Antibody (MoAb). On the other hand, JSB1 MoAb was tested in 173 of these samples. At onset, PGP was detected in 57.4% of cases with C219 and 75.9% of cases with JSB1. There was no correlation between PGP expression and...
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