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Article

Expression of some ATP-binding cassette transporters in acute myeloid leukemia

22 Dec 2017

Abstract excerpt

Hematopoietic cells express ATP binding cassette (ABC) transporters in relation to different degrees of differentiation. One of the known multidrug resistance mechanisms in acute myeloid leukemia (AML) is the overexpression of efflux pumps belonging to the superfamily of ABC transporters such as ABCB1, ABCG2 and ABCC1. Although several studies were carried out to correlate ABC transporters expression with drug...

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PMID: 29333226
DOI: 10.4081/hr.2017.7406

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