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Article

The non-coding Air RNA is required for silencing autosomal imprinted genes.

Nature - 14 Feb 2002

Sleutels Frank, Zwart Ronald, Barlow Denise P

Abstract excerpt

In genomic imprinting, one of the two parental alleles of an autosomal gene is silenced epigenetically by a cis-acting mechanism. A bidirectional silencer for a 400-kilobase region that contains three imprinted, maternally expressed protein-coding genes (Igf2r/Slc22a2/Slc22a3) has been shown by targeted deletion to be located in a sequence of 3.7 kilobases, which also contains the promoter for the imprinted,...

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PMID: 11845212
DOI: 10.1038/415810a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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